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Colin 27 Average Brain
Stereotaxic Registration Model
This is a stereotaxic average of 27 T1-weighted MRI scans of the same
individual. This average dataset was created in a two step process.
First, each of the 27 T1-weighted scans were registered to stereotaxic
space using the mritotal procedure and resampled onto a 1mm grid in
stereotaxicc space. All 27 scans were averaged together to create an
initial average. This average volume was used as a target for the
second phase of registration where each original T1-weighted MRI was
re-registered in stereotaxic space. This procedure has the advantage
of removing the small variance in intra-subject mapping in stereotaxic
space associated with the use of a multi-subject average. This
procedure has been described in detail in:
Holmes CJ, Hoge R, Collins L, Woods R, Toga AW, Evans AC.
"Enhancement of MR images using registration for signal averaging."
J Comput Assist Tomogr. 1998 Mar-Apr;22(2):324-33.
The volumes here are specially adapted for use with the MNI Linear
Registration Package (mni_autoreg). Included in this package are the
following files:
colin27_t1_tal_lin.mnc:
a version of the average of 27 scans described above. This
volume covers the whole brain (unlike the original Talairach
atlas), and is sampled with 1mm cubic voxels
colin27_t1_tal_lin_mask.mnc, colin27_t1_tal_lin_mask.obj:
a mask of the intra-cranial cavity of colin27.mnc, created
using mincbet-1.3.6 (derived from FSL Bet)
colin27_t1_tal_lin_headmask.mnc:
a rough mask of the whole head, required for nonlinear mode
colin27_t1_tal_lin_vent.mnc, colin27_t1_tal_lin_vent.obj:
a mask of the ventricles
colin_t1_tal_lin_ntags_1000_bg.tag:
tag points for the background for colin27_t1_tal_lin.mnc
colin_t1_tal_lin_ntags_1000_nobg.tag:
tag points for the CSF, GM, and WM for colin27_t1_tal_lin.mnc
Cerebellum_Ventricles_SubCortical_Mask-colin.mnc:
a template for the cerebellum, brain-stem, ventricles and sub-cortical
gray to be used in the CIVET pipeline
colin_to_icbm152_2009a.xfm, colin_to_icbm152_2009a_grid_0.mnc:
a non-linear transform to map the Colin model to the MNI-ICBM152-2009a
model.
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