diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 127dc5a38c06..daaf57f15066 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -43,6 +43,7 @@ jobs:
           - {VERSION: "3.12", NOXSESSION: "tests", OPENSSL: {TYPE: "openssl", VERSION: "3.5.0"}}
           - {VERSION: "3.12", NOXSESSION: "rust,tests", OPENSSL: {TYPE: "libressl", VERSION: "3.9.2"}}
           - {VERSION: "3.12", NOXSESSION: "rust,tests", OPENSSL: {TYPE: "libressl", VERSION: "4.0.0"}}
+          - {VERSION: "3.12", NOXSESSION: "rust,tests", OPENSSL: {TYPE: "libressl", VERSION: "4.1.0"}}
           - {VERSION: "3.12", NOXSESSION: "tests-randomorder"}
           # Latest commit on the BoringSSL main branch, as of May 02, 2025.
           - {VERSION: "3.12", NOXSESSION: "rust,tests", OPENSSL: {TYPE: "boringssl", VERSION: "e88e5069694dd6da6398dab7f020d6c271c3022f"}}