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add CHIKV DMS blog post
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posts/2025-08-18_kp311_dms.md

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author: Jesse Bloom
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In a new study led by Bernadeta Dadaonaite and [posted on bioRxiv today](https://doi.org/10.1101/2025.08.18.671001), we used pseudovirus deep mutational scanning to understand how mutations affect the fucntion and antigenicity of a recent SARS-CoV-2 variant that is fairly similar to those circulating right now.
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In a new study led by Bernadeta Dadaonaite and [posted on bioRxiv today](https://doi.org/10.1101/2025.08.18.671001), we used pseudovirus deep mutational scanning to understand how mutations affect the function and antigenicity of a recent SARS-CoV-2 variant that is fairly similar to those circulating right now.
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posts/2025-08-26_chikv_dms.md

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title: Determinants of human versus mosquito cell entry by the Chikungunya virus envelope proteins
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date: 2025-08-26
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author: Jesse Bloom
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In a new study led by Xiaohui Ju and [recently posted on bioRxiv](https://doi.org/10.1101/2025.08.25.672233), we measure how mutations the Chikungunya virus envelope proteins affect entry in human vs mosquito cells.
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The results help elucidate how this virus can infect cells from such diverse species, and enable us to create loss-of-tropism mutants that can only efficiently infect cells from one species.
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For accessible summaries of the study, see:
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- [This Bluesky thread](https://bsky.app/profile/jbloomlab.bsky.social/post/3ly2bhapxd22j), which can be read more easily in [threaded form here](https://skywriter.blue/pages/jbloomlab.bsky.social/post/3ly2bhapxd22j).
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- [This X thread](https://x.com/jbloom_lab/status/1963741826256658916).
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All the data are available for interactive visualization and download at [https://dms-vep.org/CHIKV-181-25-E-DMS/](https://dms-vep.org/CHIKV-181-25-E-DMS/).

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