diff --git a/easybuild/easyconfigs/m/manta/manta-1.6.0-GCC-10.2.0-Python-2.7.18.eb b/easybuild/easyconfigs/m/manta/manta-1.6.0-GCC-10.2.0-Python-2.7.18.eb
index 4587e8e91df..ff224b45ba2 100644
--- a/easybuild/easyconfigs/m/manta/manta-1.6.0-GCC-10.2.0-Python-2.7.18.eb
+++ b/easybuild/easyconfigs/m/manta/manta-1.6.0-GCC-10.2.0-Python-2.7.18.eb
@@ -62,9 +62,7 @@ sanity_check_paths = {
     'dirs': ['libexec'],
 }
 
-sanity_check_commands = [
-    'python %(installdir)s/bin/runMantaWorkflowDemo.py'
-]
+sanity_check_commands = ['cd "$(mktemp -d)" && runMantaWorkflowDemo.py']
 
 modextrapaths = {
     'PATH': 'libexec',
diff --git a/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2019b-Python-2.7.16.eb b/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2019b-Python-2.7.16.eb
index 8e5943d0213..2d6c80a9b71 100644
--- a/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2019b-Python-2.7.16.eb
+++ b/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2019b-Python-2.7.16.eb
@@ -41,7 +41,7 @@ sanity_check_paths = {
     'dirs': ['lib/python', 'share'],
 }
 
-sanity_check_commands = ['runMantaWorkflowDemo.py']
+sanity_check_commands = ['cd "$(mktemp -d)" && runMantaWorkflowDemo.py']
 
 modextrapaths = {
     'PATH': 'libexec',
diff --git a/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2020a-Python-2.7.18.eb b/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2020a-Python-2.7.18.eb
index 0b2b3af8477..7633e9131e0 100644
--- a/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2020a-Python-2.7.18.eb
+++ b/easybuild/easyconfigs/m/manta/manta-1.6.0-gompi-2020a-Python-2.7.18.eb
@@ -41,7 +41,7 @@ sanity_check_paths = {
     'dirs': ['lib/python', 'share'],
 }
 
-sanity_check_commands = ['runMantaWorkflowDemo.py']
+sanity_check_commands = ['cd "$(mktemp -d)" && runMantaWorkflowDemo.py']
 
 modextrapaths = {
     'PATH': 'libexec',