diff --git a/eng/native/functions.cmake b/eng/native/functions.cmake
index c926f7e6d9c977..89ae649ebd9d58 100644
--- a/eng/native/functions.cmake
+++ b/eng/native/functions.cmake
@@ -373,11 +373,11 @@ function (get_symbol_file_name targetName outputSymbolFilename)
     endif ()
 
     set(${outputSymbolFilename} ${strip_destination_file} PARENT_SCOPE)
-  else(CLR_CMAKE_HOST_UNIX)
+  elseif(CLR_CMAKE_HOST_WIN32)
     # We can't use the $<TARGET_PDB_FILE> generator expression here since
     # the generator expression isn't supported on resource DLLs.
     set(${outputSymbolFilename} $<TARGET_FILE_DIR:${targetName}>/$<TARGET_FILE_PREFIX:${targetName}>$<TARGET_FILE_BASE_NAME:${targetName}>.pdb PARENT_SCOPE)
-  endif(CLR_CMAKE_HOST_UNIX)
+  endif()
 endfunction()
 
 function(strip_symbols targetName outputFilename)
@@ -443,7 +443,9 @@ endfunction()
 function(install_with_stripped_symbols targetName kind destination)
     if(NOT CLR_CMAKE_KEEP_NATIVE_SYMBOLS)
       strip_symbols(${targetName} symbol_file)
-      install_symbol_file(${symbol_file} ${destination} ${ARGN})
+      if (NOT "${symbol_file}" STREQUAL "")
+        install_symbol_file(${symbol_file} ${destination} ${ARGN})
+      endif()
     endif()
 
     if (CLR_CMAKE_TARGET_APPLE AND ("${kind}" STREQUAL "TARGETS"))
diff --git a/src/mono/CMakeLists.txt b/src/mono/CMakeLists.txt
index d9202a9cf196e5..77b4d14346decf 100644
--- a/src/mono/CMakeLists.txt
+++ b/src/mono/CMakeLists.txt
@@ -8,6 +8,7 @@ project(mono)
 
 include(../../eng/native/configurepaths.cmake)
 include(${CLR_ENG_NATIVE_DIR}/functions.cmake)
+include(${CLR_ENG_NATIVE_DIR}/configuretools.cmake)
 
 if (MSVC)
   # Also set by configurecompiler.cmake, which isn't used by mono yet
diff --git a/src/mono/dlls/dbgshim/CMakeLists.txt b/src/mono/dlls/dbgshim/CMakeLists.txt
index adb41b47612d8d..ffb57d5a5ed7a6 100644
--- a/src/mono/dlls/dbgshim/CMakeLists.txt
+++ b/src/mono/dlls/dbgshim/CMakeLists.txt
@@ -82,4 +82,4 @@ if(CLR_CMAKE_HOST_UNIX)
 endif()
 
 target_link_libraries(dbgshim PRIVATE ${DBGSHIM_LIBRARIES} monoapi)
-install(TARGETS dbgshim DESTINATION lib)
+install_with_stripped_symbols(dbgshim TARGETS lib)
diff --git a/src/mono/dlls/mscordbi/CMakeLists.txt b/src/mono/dlls/mscordbi/CMakeLists.txt
index c570777dca93a1..b9bbbefbe6b0b3 100644
--- a/src/mono/dlls/mscordbi/CMakeLists.txt
+++ b/src/mono/dlls/mscordbi/CMakeLists.txt
@@ -153,4 +153,4 @@ if(CLR_CMAKE_HOST_UNIX)
 endif()
 
 target_link_libraries(mscordbi PRIVATE ${COREDBI_LIBRARIES} monoapi)
-install(TARGETS mscordbi DESTINATION lib)
+install_with_stripped_symbols(mscordbi TARGETS lib)
diff --git a/src/mono/mono.proj b/src/mono/mono.proj
index ec4168167b2834..96c23f094b281e 100644
--- a/src/mono/mono.proj
+++ b/src/mono/mono.proj
@@ -263,6 +263,7 @@
       <_MonoCMakeArgs Include="-DCMAKE_INSTALL_PREFIX=&quot;$(MonoObjDir.Replace('\','/'))out&quot;"/>
       <_MonoCMakeArgs Include="-DCMAKE_INSTALL_LIBDIR=lib"/>
       <_MonoCMakeArgs Include="-DCMAKE_BUILD_TYPE=$(Configuration)"/>
+      <_MonoCMakeArgs Include="-DCLR_CMAKE_KEEP_NATIVE_SYMBOLS=true" Condition="'$(KeepNativeSymbols)' == 'true'" />
       <_MonoCMakeArgs Condition="'$(CMakeArgs)' != ''" Include="$(CMakeArgs)"/>
       <_MonoCMakeArgs Condition="'$(MonoEnableLLVM)' == 'true'" Include="-DLLVM_PREFIX=$(MonoLLVMDir)\$(_MonoLLVMTargetArchitecture)" />
       <_MonoCMakeArgs Condition="'$(BuildDarwinFrameworks)' == 'true'" Include="-DBUILD_DARWIN_FRAMEWORKS=1" />
@@ -475,20 +476,19 @@
     <PropertyGroup Condition="'$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true' or '$(TargetsMacCatalyst)' == 'true'">
       <_IcuLibdir>$(PkgMicrosoft_NETCore_Runtime_ICU_Transport)/runtimes/$(TargetOS)-$(TargetArchitecture)/native/lib</_IcuLibdir>
     </PropertyGroup>
-    <ItemGroup Condition="('$(TargetsOSX)' == 'true' or '$(TargetsMacCatalyst)' == 'true') and '$(Platform)' == 'arm64'">
-      <_MonoCMakeArgs Include="-DCMAKE_OSX_ARCHITECTURES=arm64"/>
-    </ItemGroup>
     <ItemGroup Condition="'$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true'">
       <_MonoCMakeArgs Include="-DCMAKE_SYSTEM_NAME=$(_MonoCMakeSystemName)"/>
       <_MonoCMakeArgs Include="-DCMAKE_OSX_DEPLOYMENT_TARGET=$(_MonoCMakeVersionMin)" />
       <_MonoCMakeArgs Include="-DCMAKE_OSX_SYSROOT='$(_MonoCMakeSysroot)'" />
-      <_MonoCMakeArgs Condition="'$(Platform)' == 'x64'" Include="-DCMAKE_OSX_ARCHITECTURES=x86_64"/>
-      <_MonoCMakeArgs Condition="'$(Platform)' == 'x86'" Include="-DCMAKE_OSX_ARCHITECTURES=i386"/>
-      <_MonoCMakeArgs Condition="'$(Platform)' == 'arm64'" Include="-DCMAKE_OSX_ARCHITECTURES=arm64"/>
-      <_MonoCMakeArgs Condition="'$(Platform)' == 'arm'" Include="&quot;-DCMAKE_OSX_ARCHITECTURES=armv7%3Barmv7s&quot;"/>
       <_MonoCFLAGS Include="-Wl,-application_extension" />
       <_MonoCXXFLAGS Include="-Wl,-application_extension" />
     </ItemGroup>
+    <ItemGroup Condition="$([MSBuild]::IsOSPlatform('OSX'))">
+      <_MonoCMakeArgs Condition="'$(Platform)' == 'x64'" Include="-DCMAKE_OSX_ARCHITECTURES=x86_64" />
+      <_MonoCMakeArgs Condition="'$(Platform)' == 'x86'" Include="-DCMAKE_OSX_ARCHITECTURES=i386" />
+      <_MonoCMakeArgs Condition="'$(Platform)' == 'arm64'" Include="-DCMAKE_OSX_ARCHITECTURES=arm64" />
+      <_MonoCMakeArgs Condition="'$(Platform)' == 'arm'" Include="&quot;-DCMAKE_OSX_ARCHITECTURES=armv7%3Barmv7s&quot;" />
+    </ItemGroup>
     <ItemGroup Condition="'$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true' or '$(TargetsMacCatalyst)' == 'true'">
       <_MonoCMakeArgs Include="-DICU_LIBDIR=$(_IcuLibdir)"/>
       <_MonoCMakeArgs Include="-DENABLE_ICALL_EXPORT=1"/>
@@ -599,6 +599,16 @@
     </ItemGroup>
     <ItemGroup>
       <_MonoCMakeArgs Include="-DMONO_COMPONENTS_RID=$(TargetOS)-$(TargetArchitecture)" />
+
+      <!--
+        The common infra (eng/native) uses two dimensions for platform definition: host and target
+        For reasons, mono works with three dimensions: host, target and build
+        Here, we are mapping mono's three dimensions to two-dimensional system to be able to use common infra (by setting CLR_CMAKE_XXX).
+
+        See this post for understanding of cross-compilation terminologies in details: https://stackoverflow.com/a/15901574
+      -->
+      <_MonoCMakeArgs Condition="'$(TargetArchitecture)' == 'wasm'" Include="-DCLR_CMAKE_HOST_ARCH=$(BuildArchitecture)" />
+      <_MonoCMakeArgs Condition="'$(TargetArchitecture)' != 'wasm'" Include="-DCLR_CMAKE_HOST_ARCH=$(TargetArchitecture)" />
     </ItemGroup>
 
     <PropertyGroup>
@@ -651,61 +661,6 @@
     <!-- build -->
     <Message Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true'" Text="Running '$(_MonoCMakeBuildCommand)' in '$(MonoObjDir)'" Importance="High"/>
     <Exec Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true'" Command="$(_MonoCMakeBuildCommand)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)"/>
-
-    <!-- strip -->
-    <PropertyGroup>
-      <MonoToolchainPrebuiltOS Condition="$([MSBuild]::IsOSPlatform('Linux'))">linux-x86_64</MonoToolchainPrebuiltOS>
-      <MonoToolchainPrebuiltOS Condition="$([MSBuild]::IsOSPlatform('OSX'))">darwin-x86_64</MonoToolchainPrebuiltOS>
-      <MonoToolchainPrebuiltOS Condition="'$(HostOS)' == 'windows'">windows-x86_64</MonoToolchainPrebuiltOS>
-      <_MonoRuntimeFilePath>$(MonoObjDir)out\lib\$(MonoFileName)</_MonoRuntimeFilePath>
-      <_LinuxAbi Condition="'$(TargetsAndroid)' != 'true' and '$(TargetsLinuxBionic)' != 'true' and '$(TargetsLinuxMusl)' != 'true'">linux-gnu</_LinuxAbi>
-      <_LinuxAbi Condition="'$(TargetsAndroid)' != 'true' and '$(TargetsLinuxBionic)' != 'true' and '$(TargetsLinuxMusl)' == 'true'">alpine-linux-musl</_LinuxAbi>
-      <_LinuxAbi Condition="'$(TargetsAndroid)' == 'true' or '$(TargetsLinuxBionic)' == 'true'">linux-android</_LinuxAbi>
-      <_LinuxFloatAbi Condition="'$(TargetsAndroid)' != 'true' and '$(TargetsLinuxBionic)' != 'true'">hf</_LinuxFloatAbi>
-      <_Objcopy>objcopy</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 'arm'">arm-$(_LinuxAbi)eabi$(_LinuxFloatAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 'armv6'">arm-$(_LinuxAbi)eabi$(_LinuxFloatAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 'arm64'">aarch64-$(_LinuxAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 'riscv64'">riscv64-$(_LinuxAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 's390x'">s390x-$(_LinuxAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 'ppc64le'">powerpc64le-$(_LinuxAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 'x64'">x86_64-$(_LinuxAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(Platform)' == 'x86'">i686-$(_LinuxAbi)-$(_Objcopy)</_Objcopy>
-      <_Objcopy Condition="'$(TargetsAndroid)' == 'true' or '$(TargetsLinuxBionic)' == 'true'">$(ANDROID_NDK_ROOT)/toolchains/llvm/prebuilt/$(MonoToolchainPrebuiltOS)/bin/llvm-objcopy</_Objcopy>
-      <_Objcopy Condition="'$(TargetsLinuxMusl)' == 'true' and '$(CrossBuild)' != 'true'">objcopy</_Objcopy>
-
-      <_ObjcopyPrefix Condition="'$(MonoCrossDir)' != '' and '$(Platform)' == 'riscv64' and $(_Objcopy) == ''">llvm-objcopy-</_ObjcopyPrefix>
-    </PropertyGroup>
-    <!-- test viability of objcopy command -->
-    <Exec Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ('$(TargetsLinux)' == 'true' or '$(TargetsAndroid)' == 'true' or '$(TargetsLinuxBionic)' == 'true')" Command="llvm-objcopy -V" IgnoreStandardErrorWarningFormat="true" ContinueOnError="WarnAndContinue" IgnoreExitCode="true" EchoOff="true" ConsoleToMsBuild="true">
-      <Output TaskParameter="ExitCode" PropertyName="_ObjcopyFound"/>
-    </Exec>
-    <PropertyGroup>
-      <_Objcopy Condition="'$(_ObjcopyFound)' == '0'">llvm-objcopy</_Objcopy>
-    </PropertyGroup>
-    <Exec Condition="'$(_ObjcopyFound)' != '0' and '$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ('$(TargetsLinux)' == 'true' or '$(TargetsAndroid)' == 'true' or '$(TargetsLinuxBionic)' == 'true')" Command="$(_Objcopy) -V" IgnoreStandardErrorWarningFormat="true" ContinueOnError="WarnAndContinue" IgnoreExitCode="true" EchoOff="true" ConsoleToMsBuild="true">
-      <Output TaskParameter="ExitCode" PropertyName="_ObjcopyFound"/>
-    </Exec>
-    <Exec Condition="'$(_ObjcopyPrefix)' != ''" Command="find /usr/bin -name $(_ObjcopyPrefix)* | sort -V | tail -1" IgnoreStandardErrorWarningFormat="true" ContinueOnError="WarnAndContinue" IgnoreExitCode="true" EchoOff="true" ConsoleToMsBuild="true">
-      <Output TaskParameter="ExitCode" PropertyName="_ObjcopyFound"/>
-      <Output TaskParameter="ConsoleOutput" PropertyName="_Objcopy"/>
-    </Exec>
-
-    <PropertyGroup>
-      <!-- if all else fails in finding a valid objcopy, fall back to no-prefix from $PATH (used for x64 on CentOS) -->
-      <_Objcopy Condition="'$(_ObjcopyFound)' != '0'">objcopy</_Objcopy>
-    </PropertyGroup>
-    <ItemGroup Condition="'$(KeepNativeSymbols)' != 'true'" >
-      <FilesToStrip Include="$(_MonoRuntimeFilePath)" />
-      <FilesToStrip Include="$([System.IO.Directory]::GetParent($(_MonoRuntimeFilePath)))\libmono-component-*$(LibSuffix)" />
-      <FilesToStrip Include="$([System.IO.Directory]::GetParent($(_MonoRuntimeFilePath)))\Mono*framework\**\Mono*" Exclude="$([System.IO.Directory]::GetParent($(_MonoRuntimeFilePath)))\Mono*framework\**\*.dwarf" />
-    </ItemGroup>
-    <Message Condition="'@(FilesToStrip)' != '' and '$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ($([MSBuild]::IsOSPlatform('OSX')) or $([MSBuild]::IsOSPlatform('Linux')))" Text="Stripping debug symbols from %(FilesToStrip.Identity)" Importance="High"/>
-    <Exec Condition="'@(FilesToStrip)' != '' and !$([System.String]::Copy(%(FilesToStrip.Identity)).EndsWith('.a')) and '$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ('$(TargetsOSX)' == 'true' or '$(TargetsMacCatalyst)' == 'true' or '$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true')" Command="dsymutil --flat --minimize %(FilesToStrip.Identity)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)"/>
-    <Exec Condition="'@(FilesToStrip)' != '' and !$([System.String]::Copy(%(FilesToStrip.Identity)).EndsWith('.a')) and '$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ('$(TargetsOSX)' == 'true' or '$(TargetsMacCatalyst)' == 'true' or '$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true') and '$(Configuration)' == 'Release'" Command="strip -no_code_signature_warning -S %(FilesToStrip.Identity)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)"/>
-    <Exec Condition="'@(FilesToStrip)' != '' and !$([System.String]::Copy(%(FilesToStrip.Identity)).EndsWith('.a')) and '$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ('$(TargetsLinux)' == 'true' or '$(TargetsAndroid)' == 'true')" Command="$(_Objcopy) --only-keep-debug %(FilesToStrip.Identity) %(FilesToStrip.Identity).dbg" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)"/>
-    <Exec Condition="'@(FilesToStrip)' != '' and !$([System.String]::Copy(%(FilesToStrip.Identity)).EndsWith('.a')) and '$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ('$(TargetsLinux)' == 'true' or '$(TargetsAndroid)' == 'true')" Command="$(_Objcopy) --strip-unneeded %(FilesToStrip.Identity)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)"/>
-    <Exec Condition="'@(FilesToStrip)' != '' and !$([System.String]::Copy(%(FilesToStrip.Identity)).EndsWith('.a')) and '$(BuildMonoAOTCrossCompilerOnly)' != 'true' and ('$(TargetsLinux)' == 'true' or '$(TargetsAndroid)' == 'true')" Command="$(_Objcopy) --add-gnu-debuglink=%(FilesToStrip.Identity).dbg %(FilesToStrip.Identity)" IgnoreStandardErrorWarningFormat="true" WorkingDirectory="$(MonoObjDir)"/>
   </Target>
 
   <!-- Build AOT cross compiler (if available) -->
@@ -736,6 +691,12 @@
       <MonoAotAbi Condition="'$(Platform)' == 'x64'">x86_64-apple-maccatalyst</MonoAotAbi>
     </PropertyGroup>
 
+    <PropertyGroup>
+      <MonoToolchainPrebuiltOS Condition="$([MSBuild]::IsOSPlatform('Linux'))">linux-x86_64</MonoToolchainPrebuiltOS>
+      <MonoToolchainPrebuiltOS Condition="$([MSBuild]::IsOSPlatform('OSX'))">darwin-x86_64</MonoToolchainPrebuiltOS>
+      <MonoToolchainPrebuiltOS Condition="'$(HostOS)' == 'windows'">windows-x86_64</MonoToolchainPrebuiltOS>
+    </PropertyGroup>
+
     <!-- Linux specific options -->
     <ItemGroup Condition="'$(RealTargetOS)' == 'linux' or $([MSBuild]::IsOSPlatform('Linux'))">
       <_LibClang Include="$(ANDROID_NDK_ROOT)/toolchains/llvm/prebuilt/$(MonoToolchainPrebuiltOS)/lib64/libclang.so.*"/>
@@ -748,9 +709,17 @@
       <MonoAotOffsetsPrefix Condition="'$(Platform)' == 'arm64'">$(MonoCrossDir)/usr/lib/gcc/aarch64-linux-gnu/5</MonoAotOffsetsPrefix>
     </PropertyGroup>
 
+    <PropertyGroup>
+      <_MonoLLVMTargetArchitecture>$(BuildArchitecture)</_MonoLLVMTargetArchitecture>
+      <_MonoLLVMTargetArchitecture Condition="'$(RealTargetArchitecture)' != ''">$(RealTargetArchitecture)</_MonoLLVMTargetArchitecture>
+    </PropertyGroup>
+
     <!-- macOS host specific options -->
     <ItemGroup Condition="'$(RealTargetOS)' == 'osx' or $([MSBuild]::IsOSPlatform('OSX'))">
-      <MonoAOTCMakeArgs Condition="'$(RealTargetArchitecture)' == 'arm64'" Include="-DCMAKE_OSX_ARCHITECTURES=arm64"/>
+      <MonoAOTCMakeArgs Condition="'$(_MonoLLVMTargetArchitecture)' == 'x64'" Include="-DCMAKE_OSX_ARCHITECTURES=x86_64" />
+      <MonoAOTCMakeArgs Condition="'$(_MonoLLVMTargetArchitecture)' == 'x86'" Include="-DCMAKE_OSX_ARCHITECTURES=i386" />
+      <MonoAOTCMakeArgs Condition="'$(_MonoLLVMTargetArchitecture)' == 'arm64'" Include="-DCMAKE_OSX_ARCHITECTURES=arm64" />
+      <MonoAOTCMakeArgs Condition="'$(_MonoLLVMTargetArchitecture)' == 'arm'" Include="&quot;-DCMAKE_OSX_ARCHITECTURES=armv7%3Barmv7s&quot;" />
       <MonoAOTCMakeArgs Include="-DCMAKE_OSX_DEPLOYMENT_TARGET=$(macOSVersionMin)" />
       <MonoAOTCMakeArgs Include="-DENABLE_ICALL_EXPORT=1"/>
       <_MonoAOTCFLAGS Condition="'$(RealTargetArchitecture)' == 'arm64'" Include="-arch arm64" />
@@ -797,6 +766,8 @@
       <_MonoAOTCPPFLAGS Include="-DNVALGRIND" />
 
       <MonoAOTCMakeArgs Include="-DDISABLE_INTERPRETER=1" />
+      <MonoAOTCMakeArgs Condition="'$(TargetArchitecture)' == 'wasm'" Include="-DCLR_CMAKE_HOST_ARCH=$(BuildArchitecture)" />
+      <MonoAOTCMakeArgs Condition="'$(TargetArchitecture)' != 'wasm'" Include="-DCLR_CMAKE_HOST_ARCH=$(TargetArchitecture)" />
 
       <!-- Select generator platform for VS generator -->
       <MonoAOTCMakeArgs Condition="'$(_MonoUseNinja)' != 'true' and '$(Platform)' == 'x64'" Include="-A x64" />
@@ -808,9 +779,6 @@
     <!-- Android specific options -->
     <PropertyGroup Condition="'$(TargetsAndroid)' == 'true' or '$(TargetsLinuxBionic)' == 'true'">
       <_MonoSkipInitCompiler>true</_MonoSkipInitCompiler>
-      <MonoToolchainPrebuiltOS Condition="$([MSBuild]::IsOSPlatform('Linux'))">linux-x86_64</MonoToolchainPrebuiltOS>
-      <MonoToolchainPrebuiltOS Condition="$([MSBuild]::IsOSPlatform('OSX'))">darwin-x86_64</MonoToolchainPrebuiltOS>
-      <MonoToolchainPrebuiltOS Condition="'$(HostOS)' == 'windows'">windows-x86_64</MonoToolchainPrebuiltOS>
 
       <MonoUseCrossTool>true</MonoUseCrossTool>
       <MonoAotCMakeSysroot Condition="Exists('$(ANDROID_NDK_ROOT)/sysroot')">$(ANDROID_NDK_ROOT)/sysroot</MonoAotCMakeSysroot>
@@ -859,8 +827,6 @@
     <PropertyGroup>
       <_MonoAOTCFLAGSOption>-DCMAKE_C_FLAGS=&quot;@(_MonoAOTCPPFLAGS, ' ') @(_MonoAOTCFLAGS, ' ')&quot;</_MonoAOTCFLAGSOption>
       <_MonoAOTCXXFLAGSOption>-DCMAKE_CXX_FLAGS=&quot;@(_MonoAOTCPPFLAGS, ' ') @(_MonoAOTCXXFLAGS, ' ')&quot;</_MonoAOTCXXFLAGSOption>
-      <_MonoLLVMTargetArchitecture>$(BuildArchitecture)</_MonoLLVMTargetArchitecture>
-      <_MonoLLVMTargetArchitecture Condition="'$(RealTargetArchitecture)' != ''">$(RealTargetArchitecture)</_MonoLLVMTargetArchitecture>
     </PropertyGroup>
     <ItemGroup>
       <MonoAOTCMakeArgs Include="-DAOT_TARGET_TRIPLE=$(MonoAotAbi)"/>
@@ -948,8 +914,7 @@
   <!-- General targets -->
   <Target Name="BuildMono" AfterTargets="Build" DependsOnTargets="$(MonoDependsOnTargets)">
     <PropertyGroup Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true'">
-      <_MonoRuntimeFilePath Condition="'$(TargetsWindows)' == 'true'">$(MonoObjDir)out\bin\$(MonoFileName)</_MonoRuntimeFilePath>
-      <_MonoRuntimeFilePath Condition="'$(_MonoRuntimeFilePath)' == ''">$(MonoObjDir)out\lib\$(MonoFileName)</_MonoRuntimeFilePath>
+      <_MonoRuntimeFilePath>$(MonoObjDir)out\lib\$(MonoFileName)</_MonoRuntimeFilePath>
       <_MonoRuntimeStaticFilePath Condition="'$(TargetsMacCatalyst)' == 'true' or '$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true' or '$(TargetsAndroid)' == 'true' or '$(TargetsLinuxBionic)' == 'true'">$(MonoObjDir)out\lib\$(MonoStaticLibFileName)</_MonoRuntimeStaticFilePath>
       <_MonoIncludeInterpStaticFiles Condition="'$(TargetsBrowser)' == 'true' or '$(TargetsWasi)' == 'true'">true</_MonoIncludeInterpStaticFiles>
       <_MonoIncludeIcuFiles Condition="'$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true' or '$(TargetsMacCatalyst)' == 'true'">true</_MonoIncludeIcuFiles>
@@ -1101,8 +1066,6 @@
           DestinationFiles="@(_MonoRuntimeBuildArtifacts->'$(RuntimeBinDir)build\%(RecursiveDir)%(Filename)%(Extension)')"
           SkipUnchangedFiles="true"
           Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true'" />
-
-    <Exec Condition="'$(BuildMonoAOTCrossCompilerOnly)' != 'true' and '$(MonoGenerateOffsetsOSGroups)' == '' and ('$(TargetsOSX)' == 'true' or '$(TargetsMacCatalyst)' == 'true' or '$(TargetsiOS)' == 'true' or '$(TargetstvOS)' == 'true')" Command="install_name_tool -id @rpath/$(MonoFileName) $(RuntimeBinDir)$(MonoFileName)" />
   </Target>
 
   <Target Name="CleanMono">
diff --git a/src/mono/mono/component/CMakeLists.txt b/src/mono/mono/component/CMakeLists.txt
index 8a8964efc087e5..967ea555f96901 100644
--- a/src/mono/mono/component/CMakeLists.txt
+++ b/src/mono/mono/component/CMakeLists.txt
@@ -192,7 +192,7 @@ if(NOT DISABLE_COMPONENTS AND NOT STATIC_COMPONENTS)
       target_link_libraries("mono-component-${component}" PRIVATE monosgen-shared)
     endif()
     target_link_libraries("mono-component-${component}" PRIVATE ${OS_LIBS})
-    install(TARGETS "mono-component-${component}" LIBRARY)
+    install_with_stripped_symbols("mono-component-${component}" TARGETS lib)
   endforeach()
 
   #define a library for each component and component stub
diff --git a/src/mono/mono/eventpipe/test/CMakeLists.txt b/src/mono/mono/eventpipe/test/CMakeLists.txt
index 5662e9ca46a3db..34e84a77768e58 100644
--- a/src/mono/mono/eventpipe/test/CMakeLists.txt
+++ b/src/mono/mono/eventpipe/test/CMakeLists.txt
@@ -43,7 +43,7 @@ if(ENABLE_PERFTRACING)
         if(ICU_LDFLAGS)
             set_target_properties(ep-test PROPERTIES LINK_FLAGS ${ICU_LDFLAGS})
         endif()
-        install(TARGETS ep-test RUNTIME)
+        install_with_stripped_symbols(ep-test TARGETS bin)
     else(ENABLE_EVENTPIPE_TEST AND STATIC_COMPONENTS AND (NOT DISABLE_COMPONENTS) AND (NOT DISABLE_LIBS) AND (NOT DISABLE_EXECUTABLES))
         message(VERBOSE "Skip building native EventPipe library test runner.")
     endif(ENABLE_EVENTPIPE_TEST AND STATIC_COMPONENTS AND (NOT DISABLE_COMPONENTS) AND (NOT DISABLE_LIBS) AND (NOT DISABLE_EXECUTABLES))
diff --git a/src/mono/mono/metadata/CMakeLists.txt b/src/mono/mono/metadata/CMakeLists.txt
index abddf1a58a5d92..1c692c9f6f0e1f 100644
--- a/src/mono/mono/metadata/CMakeLists.txt
+++ b/src/mono/mono/metadata/CMakeLists.txt
@@ -208,4 +208,3 @@ target_compile_definitions(metadata_objects PRIVATE -DMONO_DLL_EXPORT)
 target_include_directories(metadata_objects PRIVATE ${PROJECT_BINARY_DIR}/../..
   ${PROJECT_SOURCE_DIR}/../..
   ${PROJECT_SOURCE_DIR}/..)
-
diff --git a/src/mono/mono/mini/CMakeLists.txt b/src/mono/mono/mini/CMakeLists.txt
index 8419317adc58c3..2d39b5dbe266d9 100644
--- a/src/mono/mono/mini/CMakeLists.txt
+++ b/src/mono/mono/mini/CMakeLists.txt
@@ -410,7 +410,7 @@ if(NOT DISABLE_SHARED_LIBS)
     # if components are disabled, link the fallback stubs into the runtime
     target_sources(monosgen-shared PRIVATE "${mono-components-stub-objects}")
   endif()
-  install(TARGETS monosgen-shared LIBRARY)
+  install_with_stripped_symbols(monosgen-shared TARGETS lib)
   if(HOST_WIN32 AND TARGET_AMD64)
     add_library(monosgen-shared-dac SHARED "mini-windows-dlldac.c")
     target_link_libraries(monosgen-shared-dac PRIVATE monoapi eglib_api)
@@ -452,9 +452,7 @@ if(NOT DISABLE_SHARED_LIBS)
           FRAMEWORK_VERSION C
           MACOSX_FRAMEWORK_IDENTIFIER net.dot.mono-framework
         )
-        install(TARGETS ${frameworkconfig}
-          FRAMEWORK DESTINATION ${CMAKE_INSTALL_LIBDIR}
-        )
+        install_with_stripped_symbols(${frameworkconfig} TARGETS ${CMAKE_INSTALL_LIBDIR})
       endforeach()
     endif()
   endif()
@@ -567,8 +565,5 @@ if(NOT DISABLE_EXECUTABLES)
     target_sources(mono-sgen PRIVATE ${mono_validate_apis_source})
   endif()
 
-  install(TARGETS mono-sgen RUNTIME)
-  if(HOST_WIN32)
-    install(FILES $<TARGET_PDB_FILE:mono-sgen> DESTINATION bin OPTIONAL)
-  endif()
+  install_with_stripped_symbols(mono-sgen TARGETS bin)
 endif()