diff --git a/src/coreclr/vm/readytoruninfo.cpp b/src/coreclr/vm/readytoruninfo.cpp
index eed2bf26e94b03..34cd10559aa1ba 100644
--- a/src/coreclr/vm/readytoruninfo.cpp
+++ b/src/coreclr/vm/readytoruninfo.cpp
@@ -383,6 +383,12 @@ void ReadyToRunInfo::SetMethodDescForEntryPointInNativeImage(PCODE entryPoint, M
     }
     CONTRACTL_END;
 
+    // We are entering coop mode here so that we don't do it later inside LookupMap while we are already holding the Crst.
+    // Doing it in the other order can block the debugger from running func-evals. For example thread A would acquire the Crst,
+    // then block at the coop transition inside LookupMap waiting for the debugger to resume from a break state. The debugger then
+    // requests thread B to run a funceval, the funceval tries to load some R2R method calling in here, then it blocks because
+    // thread A is holding the Crst.
+    GCX_COOP();
     CrstHolder ch(&m_Crst);
 
     if ((TADDR)m_entryPointToMethodDescMap.LookupValue(PCODEToPINSTR(entryPoint), (LPVOID)PCODEToPINSTR(entryPoint)) == (TADDR)INVALIDENTRY)
@@ -729,7 +735,7 @@ ReadyToRunInfo::ReadyToRunInfo(Module * pModule, LoaderAllocator* pLoaderAllocat
     m_pHeader(pHeader),
     m_pNativeImage(pModule != NULL ? pNativeImage: NULL), // m_pNativeImage is only set for composite image components, not the composite R2R info itself
     m_readyToRunCodeDisabled(FALSE),
-    m_Crst(CrstReadyToRunEntryPointToMethodDescMap),
+    m_Crst(CrstReadyToRunEntryPointToMethodDescMap, CRST_UNSAFE_COOPGC),
     m_pPersistentInlineTrackingMap(NULL),
     m_pNextR2RForUnrelatedCode(NULL)
 {